Routes from largest cities in North America to Little Cayman, Cayman Islands
- Mexico City, Mexico Little Cayman
- New York City, United States Little Cayman
- Los Angeles, United States Little Cayman
- Chicago, United States Little Cayman
- Toronto, Canada Little Cayman
- Brooklyn, United States Little Cayman
- Borough of Queens, United States Little Cayman
- Santo Domingo, Dominican Republic Little Cayman
- Havana, Cuba Little Cayman
- Houston, United States Little Cayman
- Iztapalapa, Mexico Little Cayman
- Ecatepec, Mexico Little Cayman
- Guadalajara, Mexico Little Cayman
- Montréal, Canada Little Cayman
- Puebla, Mexico Little Cayman
- Philadelphia, United States Little Cayman
- Ciudad Juárez, Mexico Little Cayman
- Manhattan, United States Little Cayman
- Phoenix, United States Little Cayman
- The Bronx, United States Little Cayman
- Tijuana, Mexico Little Cayman
- San Antonio, United States Little Cayman
- San Diego, United States Little Cayman
- Port-au-Prince, Haiti Little Cayman
- Ciudad Nezahualcoyotl, Mexico Little Cayman
- Santiago de los Caballeros, Dominican Republic Little Cayman
- Dallas, United States Little Cayman
- Gustavo A. Madero, Mexico Little Cayman
- Gustavo A. Madero, Mexico Little Cayman
- Monterrey, Mexico Little Cayman
- León, Mexico Little Cayman
- Calgary, Canada Little Cayman
- Guatemala City, Guatemala Little Cayman
- Zapopan, Mexico Little Cayman
- Managua, Nicaragua Little Cayman
- San Jose, United States Little Cayman
- Kingston, Jamaica Little Cayman
- Tegucigalpa, Honduras Little Cayman
- Naucalpan de Juárez, Mexico Little Cayman
- Indianapolis, United States Little Cayman
- Jacksonville, United States Little Cayman
- Ottawa, Canada Little Cayman
- Chihuahua, Mexico Little Cayman
- San Francisco, United States Little Cayman
- Austin, United States Little Cayman
- Columbus, United States Little Cayman
- Fort Worth, United States Little Cayman
- Charlotte, United States Little Cayman
- Álvaro Obregón, Mexico Little Cayman
- Guadalupe, Mexico Little Cayman
- Mérida, Mexico Little Cayman
- Tlalnepantla, Mexico Little Cayman
- Detroit, United States Little Cayman
- Edmonton, Canada Little Cayman
- Santo Domingo Oeste, Dominican Republic Little Cayman
- San Luis Potosí, Mexico Little Cayman
- Culiacán, Mexico Little Cayman
- Mississauga, Canada Little Cayman
- Aguascalientes, Mexico Little Cayman
- Acapulco de Juárez, Mexico Little Cayman
- El Paso, United States Little Cayman
- Memphis, United States Little Cayman
- New South Memphis, United States Little Cayman
- North York, Canada Little Cayman
- Winnipeg, Canada Little Cayman
- Coyoacán, Mexico Little Cayman
- Santiago de Querétaro, Mexico Little Cayman
- Saltillo, Mexico Little Cayman
- Baltimore, United States Little Cayman
- Boston, United States Little Cayman
- Seattle, United States Little Cayman
- Tlalpan, Mexico Little Cayman
- Washington, D.C., United States Little Cayman
- Denver, United States Little Cayman
- Vancouver, Canada Little Cayman
- Scarborough, Canada Little Cayman
- Mexicali, Mexico Little Cayman
- Hermosillo, Mexico Little Cayman
- Milwaukee, United States Little Cayman
- Morelia, Mexico Little Cayman
- New Kingston, Jamaica Little Cayman
- Portland, United States Little Cayman
- Las Vegas, United States Little Cayman
- Oklahoma City, United States Little Cayman
- South Boston, United States Little Cayman
- Veracruz, Mexico Little Cayman
- Santiago de Cuba, Cuba Little Cayman
- Albuquerque, United States Little Cayman
- Cancún, Mexico Little Cayman
- Nashville, United States Little Cayman
- Québec, Canada Little Cayman
- San Salvador, El Salvador Little Cayman
- Santa María Chimalhuacán, Mexico Little Cayman
- Torreon, Mexico Little Cayman
- Cuauhtémoc, Mexico Little Cayman
- Ciudad López Mateos, Mexico Little Cayman
- Tucson, United States Little Cayman
- Hamilton, Canada Little Cayman
- Toluca, Mexico Little Cayman
- Reynosa, Mexico Little Cayman
- Fresno, United States Little Cayman
- Tlaquepaque, Mexico Little Cayman
- San Pedro Sula, Honduras Little Cayman
- Tuxtla Gutiérrez, Mexico Little Cayman
- Cuautitlán Izcalli, Mexico Little Cayman
- Mixco, Guatemala Little Cayman
- Staten Island, United States Little Cayman
- Sacramento, United States Little Cayman
- Long Beach, United States Little Cayman
- Kansas City, United States Little Cayman
- Victoria de Durango, Mexico Little Cayman
- Heroica Matamoros, Mexico Little Cayman
- Venustiano Carranza, Mexico Little Cayman
- San Nicolás de los Garza, Mexico Little Cayman
- Carrefour, Haiti Little Cayman