Routes from largest cities in North America to Río Grande, Puerto Rico
- Mexico City, Mexico Río Grande
- New York City, United States Río Grande
- Los Angeles, United States Río Grande
- Chicago, United States Río Grande
- Toronto, Canada Río Grande
- Brooklyn, United States Río Grande
- Borough of Queens, United States Río Grande
- Santo Domingo, Dominican Republic Río Grande
- Havana, Cuba Río Grande
- Houston, United States Río Grande
- Iztapalapa, Mexico Río Grande
- Ecatepec, Mexico Río Grande
- Guadalajara, Mexico Río Grande
- Montréal, Canada Río Grande
- Puebla, Mexico Río Grande
- Philadelphia, United States Río Grande
- Ciudad Juárez, Mexico Río Grande
- Manhattan, United States Río Grande
- Phoenix, United States Río Grande
- The Bronx, United States Río Grande
- Tijuana, Mexico Río Grande
- San Antonio, United States Río Grande
- San Diego, United States Río Grande
- Port-au-Prince, Haiti Río Grande
- Ciudad Nezahualcoyotl, Mexico Río Grande
- Santiago de los Caballeros, Dominican Republic Río Grande
- Dallas, United States Río Grande
- Gustavo A. Madero, Mexico Río Grande
- Gustavo A. Madero, Mexico Río Grande
- Monterrey, Mexico Río Grande
- León, Mexico Río Grande
- Calgary, Canada Río Grande
- Guatemala City, Guatemala Río Grande
- Zapopan, Mexico Río Grande
- Managua, Nicaragua Río Grande
- San Jose, United States Río Grande
- Kingston, Jamaica Río Grande
- Tegucigalpa, Honduras Río Grande
- Naucalpan de Juárez, Mexico Río Grande
- Indianapolis, United States Río Grande
- Jacksonville, United States Río Grande
- Ottawa, Canada Río Grande
- Chihuahua, Mexico Río Grande
- San Francisco, United States Río Grande
- Austin, United States Río Grande
- Columbus, United States Río Grande
- Fort Worth, United States Río Grande
- Charlotte, United States Río Grande
- Álvaro Obregón, Mexico Río Grande
- Guadalupe, Mexico Río Grande
- Mérida, Mexico Río Grande
- Tlalnepantla, Mexico Río Grande
- Detroit, United States Río Grande
- Edmonton, Canada Río Grande
- Santo Domingo Oeste, Dominican Republic Río Grande
- San Luis Potosí, Mexico Río Grande
- Culiacán, Mexico Río Grande
- Mississauga, Canada Río Grande
- Aguascalientes, Mexico Río Grande
- Acapulco de Juárez, Mexico Río Grande
- El Paso, United States Río Grande
- Memphis, United States Río Grande
- New South Memphis, United States Río Grande
- North York, Canada Río Grande
- Winnipeg, Canada Río Grande
- Coyoacán, Mexico Río Grande
- Santiago de Querétaro, Mexico Río Grande
- Saltillo, Mexico Río Grande
- Baltimore, United States Río Grande
- Boston, United States Río Grande
- Seattle, United States Río Grande
- Tlalpan, Mexico Río Grande
- Washington, D.C., United States Río Grande
- Denver, United States Río Grande
- Vancouver, Canada Río Grande
- Scarborough, Canada Río Grande
- Mexicali, Mexico Río Grande
- Hermosillo, Mexico Río Grande
- Milwaukee, United States Río Grande
- Morelia, Mexico Río Grande
- New Kingston, Jamaica Río Grande
- Portland, United States Río Grande
- Las Vegas, United States Río Grande
- Oklahoma City, United States Río Grande
- South Boston, United States Río Grande
- Veracruz, Mexico Río Grande
- Santiago de Cuba, Cuba Río Grande
- Albuquerque, United States Río Grande
- Cancún, Mexico Río Grande
- Nashville, United States Río Grande
- Québec, Canada Río Grande
- San Salvador, El Salvador Río Grande
- Santa María Chimalhuacán, Mexico Río Grande
- Torreon, Mexico Río Grande
- Cuauhtémoc, Mexico Río Grande
- Ciudad López Mateos, Mexico Río Grande
- Tucson, United States Río Grande
- Hamilton, Canada Río Grande
- Toluca, Mexico Río Grande
- Reynosa, Mexico Río Grande
- Fresno, United States Río Grande
- Tlaquepaque, Mexico Río Grande
- San Pedro Sula, Honduras Río Grande
- Tuxtla Gutiérrez, Mexico Río Grande
- Cuautitlán Izcalli, Mexico Río Grande
- Mixco, Guatemala Río Grande
- Staten Island, United States Río Grande
- Sacramento, United States Río Grande
- Long Beach, United States Río Grande
- Kansas City, United States Río Grande
- Victoria de Durango, Mexico Río Grande
- Heroica Matamoros, Mexico Río Grande
- Venustiano Carranza, Mexico Río Grande
- San Nicolás de los Garza, Mexico Río Grande
- Carrefour, Haiti Río Grande