Routes from largest cities in North America to San Francisco, Panama
- Mexico City, Mexico San Francisco
- New York City, United States San Francisco
- Los Angeles, United States San Francisco
- Chicago, United States San Francisco
- Toronto, Canada San Francisco
- Brooklyn, United States San Francisco
- Borough of Queens, United States San Francisco
- Santo Domingo, Dominican Republic San Francisco
- Havana, Cuba San Francisco
- Houston, United States San Francisco
- Iztapalapa, Mexico San Francisco
- Ecatepec, Mexico San Francisco
- Guadalajara, Mexico San Francisco
- Montréal, Canada San Francisco
- Puebla, Mexico San Francisco
- Philadelphia, United States San Francisco
- Ciudad Juárez, Mexico San Francisco
- Manhattan, United States San Francisco
- Phoenix, United States San Francisco
- The Bronx, United States San Francisco
- Tijuana, Mexico San Francisco
- San Antonio, United States San Francisco
- San Diego, United States San Francisco
- Port-au-Prince, Haiti San Francisco
- Ciudad Nezahualcoyotl, Mexico San Francisco
- Santiago de los Caballeros, Dominican Republic San Francisco
- Dallas, United States San Francisco
- Gustavo A. Madero, Mexico San Francisco
- Gustavo A. Madero, Mexico San Francisco
- Monterrey, Mexico San Francisco
- León, Mexico San Francisco
- Calgary, Canada San Francisco
- Guatemala City, Guatemala San Francisco
- Zapopan, Mexico San Francisco
- Managua, Nicaragua San Francisco
- San Jose, United States San Francisco
- Kingston, Jamaica San Francisco
- Tegucigalpa, Honduras San Francisco
- Naucalpan de Juárez, Mexico San Francisco
- Indianapolis, United States San Francisco
- Jacksonville, United States San Francisco
- Ottawa, Canada San Francisco
- Chihuahua, Mexico San Francisco
- San Francisco, United States San Francisco
- Austin, United States San Francisco
- Columbus, United States San Francisco
- Fort Worth, United States San Francisco
- Charlotte, United States San Francisco
- Álvaro Obregón, Mexico San Francisco
- Guadalupe, Mexico San Francisco
- Mérida, Mexico San Francisco
- Tlalnepantla, Mexico San Francisco
- Detroit, United States San Francisco
- Edmonton, Canada San Francisco
- Santo Domingo Oeste, Dominican Republic San Francisco
- San Luis Potosí, Mexico San Francisco
- Culiacán, Mexico San Francisco
- Mississauga, Canada San Francisco
- Aguascalientes, Mexico San Francisco
- Acapulco de Juárez, Mexico San Francisco
- El Paso, United States San Francisco
- Memphis, United States San Francisco
- New South Memphis, United States San Francisco
- North York, Canada San Francisco
- Winnipeg, Canada San Francisco
- Coyoacán, Mexico San Francisco
- Santiago de Querétaro, Mexico San Francisco
- Saltillo, Mexico San Francisco
- Baltimore, United States San Francisco
- Boston, United States San Francisco
- Seattle, United States San Francisco
- Tlalpan, Mexico San Francisco
- Washington, D.C., United States San Francisco
- Denver, United States San Francisco
- Vancouver, Canada San Francisco
- Scarborough, Canada San Francisco
- Mexicali, Mexico San Francisco
- Hermosillo, Mexico San Francisco
- Milwaukee, United States San Francisco
- Morelia, Mexico San Francisco
- New Kingston, Jamaica San Francisco
- Portland, United States San Francisco
- Las Vegas, United States San Francisco
- Oklahoma City, United States San Francisco
- South Boston, United States San Francisco
- Veracruz, Mexico San Francisco
- Santiago de Cuba, Cuba San Francisco
- Albuquerque, United States San Francisco
- Cancún, Mexico San Francisco
- Nashville, United States San Francisco
- Québec, Canada San Francisco
- San Salvador, El Salvador San Francisco
- Santa María Chimalhuacán, Mexico San Francisco
- Torreon, Mexico San Francisco
- Cuauhtémoc, Mexico San Francisco
- Ciudad López Mateos, Mexico San Francisco
- Tucson, United States San Francisco
- Hamilton, Canada San Francisco
- Toluca, Mexico San Francisco
- Reynosa, Mexico San Francisco
- Fresno, United States San Francisco
- Tlaquepaque, Mexico San Francisco
- San Pedro Sula, Honduras San Francisco
- Tuxtla Gutiérrez, Mexico San Francisco
- Cuautitlán Izcalli, Mexico San Francisco
- Mixco, Guatemala San Francisco
- Staten Island, United States San Francisco
- Sacramento, United States San Francisco
- Long Beach, United States San Francisco
- Kansas City, United States San Francisco
- Victoria de Durango, Mexico San Francisco
- Heroica Matamoros, Mexico San Francisco
- Venustiano Carranza, Mexico San Francisco
- San Nicolás de los Garza, Mexico San Francisco
- Carrefour, Haiti San Francisco